Sildenafil is a PDE-5 inhibitor (phosphodiesterase type 5 inhibitor), which means it blocks the effects of the PDE enzyme, relaxing the blood vessels in the penis and helping to increase blood flow. This can help men to achieve and maintain an erection hard enough for sex. Sildenafil tablets are effective in around 60-70% of men when taken as prescribed.
Possible side effects
An evaluation of visual function at doses up to twice the maximum recommended dose revealed no effects of VIAGRA on visual acuity, intraocular pressure, or pupillometry. There is a potential for cardiac risk of sexual activity inpatients with preexisting cardiovascular disease. Therefore, treatments for erectile dysfunction, BUY XANAX WITHOUT PRESCRITION including VIAGRA, should not be generally used in men forwhom sexual activity is inadvisable because of their underlying cardiovascular status.
Adverse Reactions With The Concomitant Use Of Ritonavir
The mean steady state volume of distribution (Vss) for sildenafil is 105 L, indicating distribution into the tissues. Sildenafil and its major circulating N-desmethyl metabolite are both approximately 96% bound to plasma proteins. Three double-blind, placebo-controlled, randomized, two-way crossover studies were conducted to assess the interaction of VIAGRA with doxazosin, an alphaadrenergic blocking agent. No evidence of teratogenicity, embryotoxicity or fetotoxicitywas observed in rats and rabbits which received up to 200 mg/kg/day duringorganogenesis.
Sildenafil is primarily used for the treatment of erectile dysfunction in men. Keep this medication in the container it came in, tightly closed, and out of reach of children. Store the tablets at room temperature and away from excess heat and moisture (not in the bathroom). Store the suspension at room temperature or in a refrigerator, but do not freeze it.
VIAGRA is not for use in women or children.
This is to make sure they are safe for you to take, taking into account any underlying health conditions you have or other medication you may be on. You can go to your GP for this or get Sildenafil online by simply filling out our quick consultation for fast, discreet service. Finally, the use of vacuum erection or implant devices can be an option for some men. Please speak to your GP for more information on these alternative treatment options. It can also be used in the management of finger or toe ulcers and lung conditions. Call your doctor if you have any unusual problems while you are taking this medication.
In addition, N-desmethyl metabolite AUC and C values significantly increased by 200% and 79%, respectively in subjects with severe renal impairment compared to subjects with normal renal function. Maximum observed plasma concentrations are reached within 30 to 120 minutes (median 60 minutes) of oral dosing in the fasted state. When VIAGRA is taken with a high fat meal, the rate of absorption is reduced, with a mean delay in T of 60 minutes and a mean reduction in Cmax of 29%.
ED can be a symptom of other health issues and is often experienced by people who have underlying health problems such as heart disease, type 2 diabetes, high blood pressure, high cholesterol or depression. Smokers are at higher risk than non-smokers of experiencing erectile dysfunction. Reduced flexibility and blood flow in the arteries is the main underlying physical factor. Men who drink large amounts of alcohol are also at increased risk of erectile dysfunction. If you are taking sildenafil to treat erectile dysfunction, follow your doctor’s directions and the guidelines in this paragraph.